Endocrine Abstracts

Purpose: The purpose of this study was to analyse ghrelin concentrations in the umbilical cord of pregnant women with a diagnosis of gestational diabetes mellitus. The relationship between ghrelin concentrations and birth weights was investigated.Materials and methods: Sixty pregnant women with gestational diabetes mellitus and 64 healthy pregnant women with three oral glucose tolerance test results within normal limits were included in the study. Follow...

Aim: In this case report we present a newly diagnosed, underweight type 1 diabetes mellitus (DM) patient developed insulin oedema following high dose insulin therapy.Case: A 18-year-old male patient was admitted to the hospital with a 1-month history of excessive water consumption, pollakiuria, polyuria, and weight loss 6 kg. In laboratory examination, hyperglycaemia and ketonuria were detected; arterial blood pH was 7.38. Patient was hospitalised to the...

Aim: Cardiovascular morbidity and mortality of obesity is associated with classic risk factors, namely dyslipidaemia, hypertension and impaired glucose metabolism. Aim of this study is to evaluate inflammation as an independent risk factor by using neutrophil to lymphocyte ratio (NLR).Materials and methods: Patients who admitted to our outpatient clinic between January and December 2014 were assessed retrospectively. Patients diagnosed as diabetes, predi...

Aim: To evaluate serum (SMK) and nodular (NMK) midkine levels in thyroid nodules and explore its relevance to ultrasound feature/pathological results.Methods: A total of 80 patients (56 women, 24 men) with thyroid nodules were included in this prospective study. Hemograms, thyroid function tests, fine needle aspiration biopsies, ultrasonographic evaluation were routinely made. In addition, levels of SMK and NMK were measured. Any possible correlations be...

Introduction: Although, vitamin D (vit D) mainly regulates calcium and phosphate metabolisms, its deficiency may also contribute to the development of some carcinomas, autoimmune, and cardiac diseases. Vit D deficiency has been defined to correlate with increased autoimmune disease such as type 1 diabetes mellitus, rheumatoid arthritis, autoimmune thyroid diseases (AITD). Previous studies suggested that patients with AITD had lower vit D levels when compared with healthy contr...

Aim: Hyperinsulinaemia is frequent finding in patients with hyperprolactinemia and has associations with thyroid volume. In this study, we evaluated the association between thrombotic markers, insulin resistance, CIMT, and thyroid volume in female patients with prolactinoma.Material and methods: 38 women with prolactinoma and 24 healthy women were included to the study. We evaluated anthropometric, biochemical, hematologic and hormonal parameters as well...

Introduction: Acromegaly is a chronic disease caused by excessive secretion of growth hormone (GH), and as a result, of insulin-like growth factor-1 (IGF1). Although controversial, frequency of both benign and malignant neoplasm formation is thought to be increased in acromegalic patients. Pleomorphic adenoma is the most common arising tumour from the parotid salivary gland. Here we report the case of a 33-year-old woman with acromegaly and also who presented with a swelling o...

Introduction: We report a case with primary adrenocortical deficiency after the first month of lactation.Case report: Thirty-year-old woman was referred with complaints including dizziness, weakness and fatigue in the early postpartum and lactation period. On physical examination, weight 63 kg, height 164 cm, blood pressure 100/65 mmHg, pulse 96 per min were detected. She had the increase of the brown pigmentation on her hands and face. In the a...

Aim: Patients with hypoparatiroidism may admit to hospitals with different symptoms.In this report we presented 3 case of hypoparatiroidism with congestive heart failure,epilepsy and muscle pain.Case 1: 31-year-old male admitted to hospital with dyspnea on lying down and evaluation revealed pericardial and pleural effusion. The patient was hospitalized to cardiology clinic with a prediagnosis of decompansated heart failure. In echocardiography ejection f...

Aim: Thyroid hormones act both insulin agonistic and antagonistic in different organs. Studies that evaluate the relationship between insulin resistance and hypo-hyperthyroidism have conflicting results, even euthyroid status was shown to change insulin sensitivity. In this study, our aim is to investigate the association between TSH, free T4, free T3 levels and insulin resistance in euthyroid patients.Method: Euthyroid 57 males, 47...